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Figure 4 | BMC Systems Biology

Figure 4

From: Analysis of Wnt signaling β-catenin spatial dynamics in HEK293T cells

Figure 4

Quantification of β-catenin and N-cadherin in stimulated/inhibited HEK293T cells. HEK293T cells were stimulated with Wnt3A CM or inhibited by CHX for 0, 1, 2, or 4 hours. (A) Relative change in β-catenin concentration intensity (in terms of % of T0); (B) Relative change in β-catenin compartment concentration intensity (in terms of % of T0); (C) β-catenin Nucleus/Cytosol-membrane intensity ratio (normalized to T0); (D) Relative change in N-cadherin concentration intensity (in terms of % of T0); Error Bars: (A and D) Standard deviations, (B and C) Standard Error of the Mean. n = 3; each data point has ≥ 3 image sets. A single factor analysis of variance (ANOVA) test was applied to test for differences between data points for each perturbation, specifically between T0-T240, T0-T60 and T60-T240.

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