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Figure 1 | BMC Systems Biology

Figure 1

From: Non-stationary 13C metabolic flux analysis of Chinese hamster ovary cells in batch culture using extracellular labeling highlights metabolic reversibility and compartmentation

Figure 1

Non-compratmented (A) and compartmented (B) networks of the CHO-K1 central metabolism used for simulations. Irreversibility is indicated by simple arrows, and reversibility by double arrows. The reactions depicted in 1B are listed in detail in the Additional file 1 together with fluxes and reversibilities determined. Subscripts meaning: ex – extracellular; c – cytosolic; m – mitochondrial. Abbreviations: AA –amino acids; AcoA – acetyl CoA; AKG – alpha-ketoglutarate; ALA – alanine; ASN – asparagine; ASP – aspartate; CIT/ICI – citrate/isocitrate; G6P – glucose 6-phosphate; GLC – glucose; GLN – glutamine; GLU – glutamate; GLY – glycine; MAL – malate; OAA – oxaloacetate; PEP – phosphoenolpyruvate; PG – phosphoglycerate; PYR – pyruvate; SER – serine.

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BMC Systems Biology

ISSN: 1752-0509

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