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Figure 6 | BMC Systems Biology

Figure 6

From: Stabilization of perturbed Boolean network attractors through compensatory interactions

Figure 6

The modified reduced T-LGL network. The 6 node reduced network is adapted from [34]. Red dashed lines indicate negative regulation while solid black lines indicate positive regulation. The bold line represents a possible modification that eliminates the Apoptosis = OFF (cancerous) steady state. The full names corresponding to the abbreviated node labels are (see [34]): S1P, Sphingosine-1-phosphate; DISC, death inducing signaling complex; FLIP, CASP8 and FADD-like apoptosis regulator.

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