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Figure 5 | BMC Systems Biology

Figure 5

From: In silico modeling of the effects of alpha-synuclein oligomerization on dopaminergic neuronal homeostasis

Figure 5

Graphical representation of the model structure in SBGN for the Proteasome related ASYN dynamics sub-model. Both WT (WTasyn, Figure 5A) and DA-modified (DopModWTasyn, Figure 5B) ASYN species bind to the Proteasome (blue colored reactions) and are then degraded by releasing it (red colored reactions). Also HMW ASYN species can bind to the Proteasome, however in an irreversible way.

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BMC Systems Biology

ISSN: 1752-0509

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