Table 2 Pathways with significant dysregulation in long-lived D. melanogaster
Pathway | P* | Up* | No_ch* | Down* |
|---|---|---|---|---|
Starch and sucrose metabolism | 2.71E-03 | 6 | 11 | 1 |
Circadian rhythm - fly | 7.90E-03 | 3 | 5 | 0 |
Glycerophospholipid metabolism | 1.02E-02 | 9 | 25 | 3 |
Tyrosine metabolism | 1.44E-02 | 4 | 5 | 0 |
Nicotinate and nicotinamide metabolism | 2.23E-02 | 3 | 6 | 0 |
Glycine, serine and threonine metabolism | 2.97E-02 | 4 | 14 | 3 |
Jak-STAT signaling pathway | 3.15E-02 | 1 | 11 | 2 |
Ubiquinone and other terpenoid-quinone biosynthesis | 3.26E-02 | 7 | 4 | 0 |
Endocytosis | 4.52E-02 | 6 | 16 | 1 |
Purine metabolism | 4.87E-02 | 23 | 49 | 9 |