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Figure 8 | BMC Systems Biology

Figure 8

From: Insight into model mechanisms through automatic parameter fitting: a new methodological framework for model development

Figure 8

Comparison of simulation results from the first iteration with the target output metrics. Results from a PCA of the simulations based on Table 1 (grey), together with the results from the Land-model (red). The 20 simulations closest to the target are marked with circles in cyan. The corresponding 20 parameter sets were used together with the parameter prediction from the inverse metamodelling to find new parameter ranges and generate a new experimental design for simulations with the Niederer-model.

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