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Table 2 Truth table of a PBN for the p53-Mdm2 network: x 1 , x 2 are the present states of p53 and Mdm2

From: Gene perturbation and intervention in context-sensitive stochastic Boolean networks

x 1 x 2

f 1 1

f 2 1

f 3 1

f 4 1

f 1 2

f 2 2

f 3 2

f 4 2

00

1

1

1

0

0

0

0

1

01

1

1

0

0

0

0

1

1

10

0

0

1

1

1

1

0

0

11

0

1

1

1

1

0

0

0

c j i

0.5

0.4

0.09

0.01

0.5

0.4

0.09

0.01

  1. An internal entry indicates whether a logical 1 or 0 would result at the next state of a gene from a selected Boolean function. c j i indicates the transition probability by a function f j i [24].