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Table 5 Differences in the steady state distributions (SSDs) computed using the context-sensitive stochastic Boolean network (CSSBN) model, compared to the results by using the approximate[20] and accurate analysis[23]

From: Gene perturbation and intervention in context-sensitive stochastic Boolean networks

   p = 0.01 p = 0.1 p = 0.3
    q = 0.9 q = 0.8 q = 0.9
||Δ SSD AP - AC ||1   0.0228 0.0214 0.0041
||Δ SSD CSSBN - AC ||1 L (bits) 10k 0.0094 0.0099 0.0073
50k 0.0061 0.0060 0.0057
100k 0.0047 0.0056 0.0040
||Δ SSD AP - AC ||2   0.0118 0.0118 0.0025
||Δ SSD CSSBN - AC ||2 L (bits) 10k 0.0055 0.0057 0.0041
50k 0.0036 0.0036 0.0030
100k 0.0028 0.0031 0.0025
||Δ SSD AP - AC ||∞   0.0074 0.0081 0.0020
||Δ SSD CSSBN - AC ||∞ L (bits) 10k 0.0047 0.0045 0.0027
50k 0.0030 0.0029 0.0021
   100k 0.0020 0.0022 0.0017
  1. Δ SSD AP - AC : the difference between the results obtained by using the approximate and accurate analysis. Δ SSD CSSBN - AC : the difference between the results obtained by using the CSSBN approach and the accurate analysis. p: perturbation rate, q: context switching probability, L: sequence length.
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BMC Systems Biology

ISSN: 1752-0509

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