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Table 3 GO Enrichment of YNG and MID clusters in the integrated network

From: Identifying aging-related genes in mouse hippocampus using gateway nodes

Age

Annotation

GO Term ID

Observed

P-value

Enrichment

YNG

positive regulation of biological process

GO:0048518

43

0.0300

up

response to stimulus

GO:0050896

41

0.0492

up

plasma membrane part

GO:0044459

25

0.0329

up

small molecule metabolic process

GO:0044281

20

0.0471

up

apoptosis

GO:0006915

18

0.0356

up

programmed cell death

GO:0012501

18

0.0356

up

homeostatic process

GO:0042592

11

0.0226

up

positive regulation of cell death

GO:0010942

10

0.0343

up

positive regulation of apoptosis

GO:0043065

9

0.0150

up

positive regulation of programmed cell death

GO:0043068

9

0.0150

up

MID

organelle part

GO:0044422

23

0.0482

up

intracellular organelle part

GO:0044446

21

0.0338

up

catalytic activity

GO:0003824

16

0.0222

up

plasma membrane

GO:0005886

16

0.0476

up

regulation of biological quality

GO:0065008

15

0.0033

up

plasma membrane part

GO:0044459

14

0.0100

up

positive regulation of metabolic process

GO:0009893

11

0.0221

down

protein complex

GO:0043234

11

0.0280

up

regulation of transcription from RNA polymerase II promoter

GO:0006357

10

0.0386

down

 

transcription from RNA polymerase II promoter

GO:0006366

10

0.0386

down

  1. Observed column represents the number of genes in the network with the specified annotation.