Skip to main content

Table 6 Distribution of essential, drug target and classical cancer proteins in HSN zones

From: Modelling human protein interaction networks as metric spaces has potential in disease research and drug target discovery

Zone Essential Drug Oncogenes Tumour
  roles targets   suppressors
1 157 (36.4%) 69 (16%) 12 (2.7%) 12 (2.7%)
2 815 (23.1%) 291 (8.2%) 33 (0.9%) 41 (1.1%)
3 268 (13.8%) 103 (5.3%) 4 (0.02%) 4 (0.2%)
4 29 (14%) 5 (2.4%) - -
5 4 (10.5%) 1 (2.6%) - 1 (2.6%)