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Table 8 HSN distribution of proteins consistently expressed in cancer samples

From: Modelling human protein interaction networks as metric spaces has potential in disease research and drug target discovery

Type of cancer

# proteins

Zone 1

Zone 2

Zone 3

Zone 4

Zone 5

Zone 6

Breast

236

12 (5%)

151 (63.9%)

70 (29.6%)

2 (0.8%)

1 (0.4%)

-

Cervical

533

42 (7.8%)

323 (60.6%)

157 (29.4%)

9 (1.6%)

1 (0.1%)

1 (0.1%)

Endometrial

1092

89 (8.1%)

647 (59.2%)

336 (30.7%)

17 (1.5%)

2 (0.1%)

1 (0.09%)

Fallopian

941

72 (7.6%)

563 (59.8%)

287 (30.4%)

16 (1.7%)

2 (0.2%)

1 (0.1%)

Glioblastoma

767

64 (8.3%)

471 (61.4%)

216 (28.1%)

13 (1.6%)

2 (0.2%)

1 (0.1%)

Glioma

824

35 (8%)

278 (64%)

114 (62.2%)

5 (1.1%)

1 (0.2%)

1 (0.2%)

Kidney

434

14 (2.4%)

331 (59%)

193 (34.4%)

23 (4%)

-

-

Liver

537

45 (8.3%)

328 (61%)

155 (28.8%)

7 (1.3%)

1 (0.1%)

1 (0.1%)

Lung

422

31 (7.3%)

260 (61.6%)

121 (28.6%)

8 (1.9%)

2 (0.4%)

-

Ovarian

557

39 (7%)

334 (59.9%)

174 (31.2%)

8 (1.4%)

1 (0.1%)

1 (0.1%)

Pancreatic

536

46 (8.5%)

332 (61.9%)

148 (27.6%)

8 (1.4%)

1 (0.1%)

1 (0.1%)

Pituitary

789

56 (7%)

458 (58%)

253 (32%)

19 (2.4%)

2 (0.2%)

1 (0.1%)

Rectal

1162

95 (8.1%)

677 (58.2%)

365 (31.4%)

21 (1.8%)

3 (0.2%)

1 (0.8%)

Average

 

7.5%

60.6%

29.6%

1.5%

0.2%

0.1%