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Figure 3 | BMC Systems Biology

Figure 3

From: Network-dosage compensation topologies as recurrent network motifs in natural gene networks

Figure 3

The parameter quantifying the nonlinearity of interaction between the network components is strongly constrained in dosage-invariant inducible networks. A. Histogram of the value of the sampled parameter β in dosage-invariant inducible networks having the topology of Figure 1B (green area in Figure S2D, N = 6746). B. Histogram of the value of sampled parameter α in dosage-invariant inducible networks having the topology of Figure 1C (green area in Figure S2E, N = 6124). C-D. Plot of the network compensation penalty versus the value of the strongly constrained network parameter, for networks that are both inducible and dosage invariant.

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