Improvement of experimental testing and network training conditions with genome-wide microarrays for more accurate predictions of drug gene targets

Table 4 Comparison of rank changes (RCs) for ERG11 in network training phase

RCs were reported for ERG11 across 5 FL treatment experiments, under 3 different training compendiums: + Δerg11/ERG11, + Δerg6, and + FL treatment. Percentile of RC was computed as the percentage of genes with a RC as high or higher than the target gene. RC percentiles ≥95 indicated significant perturbation as identified by SSEM-Lasso.

ISSN: 1752-0509