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Table 4 Comparison of rank changes (RCs) for ERG11 in network training phase

From: Improvement of experimental testing and network training conditions with genome-wide microarrays for more accurate predictions of drug gene targets

  ERG11
  + Δerg11/ERG11 + Δerg6 + FL
Expt analyzed Rank change (RC) Percentile Rank change (RC) Rank change (RC)
FLGI10, 1DT 488 97 −82 −75
FLGI10, 4DT 344 92 −45 142
FL GI20, 4DT 585 96 −136 −98
FL GI30, 4DT 301 88 −41 −21
FL GI40, 4DT 421 94 −70 −37
  1. RCs were reported for ERG11 across 5 FL treatment experiments, under 3 different training compendiums: + Δerg11/ERG11, + Δerg6, and + FL treatment. Percentile of RC was computed as the percentage of genes with a RC as high or higher than the target gene. RC percentiles ≥95 indicated significant perturbation as identified by SSEM-Lasso.