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Table 5 Comparison of rank changes (RCs) for ERG6 in network training phase

From: Improvement of experimental testing and network training conditions with genome-wide microarrays for more accurate predictions of drug gene targets

  ERG6
  + Δerg6 + Δerg11/ERG11 + FL
Expt analyzed Rank change (RC) Percentile Rank change (RC) Percentile Rank change (RC)
FLGI10, 1DT 3795 100 139 73 −292
FLGI10, 4DT 748 98 71 43 102
FL GI20, 4DT 999 99 99 57 6
FL GI30, 4DT 677 97 70 47 54
FL GI40, 4DT 123 48 67 45 52
  1. RCs were reported for ERG6 across 5 FL treatment experiments, under 3 different training compendiums: + Δerg6, + Δerg11/ERG11, and + FL treatment. Percentile of RC was computed as the percentage of genes with a RC as high or higher than the target gene. RC percentiles ≥95 indicated significant perturbation as identified by SSEM-Lasso.