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Table 6 Comparison of rank changes (RCs) for ERG5 in network training phase

From: Improvement of experimental testing and network training conditions with genome-wide microarrays for more accurate predictions of drug gene targets

  ERG5
  + Δhem1 + Δerg11/ERG11 + FL
Expt analyzed Rank change (RC) Percentile Rank change (RC) Rank change (RC)
FLGI10, 1DT 569 97 23 −230
FLGI10, 4DT 199 75 16 −80
FLGI20, 4DT 1064 97 −5 −656
FLGI30, 4DT 828 95 −6 −444
FLGI40, 4DT 547 90 26 −251
  1. RCs were reported for ERG5 across 5 FL treatment experiments, under 3 different training compendiums: + Δhem1, + Δerg11/ERG11, and + FL treatment. Percentile of RC was computed as the percentage of genes with a RC as high or higher than the target gene. RC percentiles ≥95 indicated significant perturbation as identified by SSEM-Lasso.