Figure 10

The complex species EGFR and its binding sites and molecule component statuses. The complex species EGFR has five binding sites, four of them (e.g. with indices 1 – 4) can be used to bind adaptors. Three molecule component states, “bndPLCg992”, “bndPLCg1173” and “bndSHC1148” accommodate the binding constraints reported in [23], which are described as rules defining which adaptors can bind simultaneously to the EGFR.