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Table 1 Survey of recent E. coli genome-scale model statistics

From: A genome-scale metabolic flux model of Escherichia coli K–12 derived from the EcoCyc database

Statistics Feist et al.[5] Orth et al.[6] EcoCyc–18.0–GEM
  2007 2011  
# Genes 1260 1366 1445
# Unique reactions 1721 1863 2286
# Unique metabolites 1039 1136 1453
Gene knockout accuracy 91.4% 91.3% 95.2%
# PM growth conditions 170 431
PM growth condition 75.9% 80.7%
accuracy    
# biomass metabolites 65 72 108
  1. Gene knockout prediction accuracy represents simulated growth on glucose minimal media under aerobic conditions. Reaction and metabolite counts represent reactions found in the cytosol and periplasm, since EcoCyc–18.0–GEM does not cover porin-mediated diffusion of metabolites into the periplasmic space.