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Table 1 Survey of recent E. coli genome-scale model statistics

From: A genome-scale metabolic flux model of Escherichia coli K–12 derived from the EcoCyc database

Statistics

Feist et al.[5]

Orth et al.[6]

EcoCyc–18.0–GEM

 

2007

2011

 

# Genes

1260

1366

1445

# Unique reactions

1721

1863

2286

# Unique metabolites

1039

1136

1453

Gene knockout accuracy

91.4%

91.3%

95.2%

# PM growth conditions

170

431

PM growth condition

75.9%

80.7%

accuracy

   

# biomass metabolites

65

72

108

  1. Gene knockout prediction accuracy represents simulated growth on glucose minimal media under aerobic conditions. Reaction and metabolite counts represent reactions found in the cytosol and periplasm, since EcoCyc–18.0–GEM does not cover porin-mediated diffusion of metabolites into the periplasmic space.