Table 2 Flux comparison between EcoCyc–18.0–GEM and iJO1366: ATP maximization objective under aerobic conditions
From: A genome-scale metabolic flux model of Escherichia coli K–12 derived from the EcoCyc database
EcoCyc | iJO1366 | ||
|---|---|---|---|
Reaction | Flux | Reaction | Flux |
ATP maximization objective | 216 | ATPM | 235 |
Glucose uptake | 10 | EX_glc(e) | 10 |
O 2 uptake | 60 | EX_o2(e) | 60 |
H 2O production | 60 | EX_h2o(e) | 60 |
CO 2 production | 60 | EX_co2(e) | 60 |
ATP synthase* | 176 | ATPS4rpp | 195 |
NADH-DEHYDROG-A-RXN | 100 | NADH16pp | 100 |
Cytochrome bo oxidase* | 60 | CYTBO3_4pp | 120 |
PYRNUTRANSHYDROGEN-RXN | 20 | NADTRHD | 20 |
GAPOXNPHOSPHN-RXN | 20 | GAPD | 20 |
ISOCITDEH-RXN | 20 | ICDHyr | 20 |
3PGAREARR-RXN | 20 | ENO | 20 |
ACONITATEDEHYDR-RXN | 20 | ACONTa/b | 20 |
PHOSGLYPHOS-RXN | 20 | PGK | 20 |
CITSYN-RXN | 20 | CS | 20 |
2OXOGLUTARATEDEH-RXN | 20 | AKGDH | 20 |
2PGADEHYDRAT-RXN | 20 | ENO | 20 |
Succinate dehydrogenase* | 20 | SUCDi | 20 |
MALATE-DEH-RXN | 20 | MDH | 20 |
FUMHYDR-RXN | 20 | FUM | 20 |
PYRUVDEH-RXN | 20 | PDH | 20 |
SUCCOASYN-RXN | 20 | SUCOAS | 20 |
PGLUCISOM-RXN | 10 | PGI | 10 |
Glucose PTS uptake* | 10 | GLCptspp | 10 |
TRIOSEPISOMERIZATION-RXN | 10 | TPI | 10 |
RXN0-313 | 10 | F6PA | 10 |
2.7.1.121-RXN | 10 | DHAPT | 10 |