Table 6 Comparison of experimental gene essentiality results with computational EcoCyc–18.0–GEM results for aerobic growth on MOPS medium with 1% glycerol
From: A genome-scale metabolic flux model of Escherichia coli K–12 derived from the EcoCyc database
KO growth on glycerol (sim/exp) | BC | BE | NC | NE |
|---|---|---|---|---|
True positive (growth/growth) | 1165 | 1124 | 1195 | 1154 |
False positive (growth/no growth) | 58 | 63 | 28 | 35 |
False negative (no growth/growth) | 22 | 63 | 102 | 143 |
True negative (no growth/no growth) | 200 | 195 | 120 | 113 |