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Table 6 Comparison of experimental gene essentiality results with computational EcoCyc–18.0–GEM results for aerobic growth on MOPS medium with 1% glycerol

From: A genome-scale metabolic flux model of Escherichia coli K–12 derived from the EcoCyc database

KO growth on glycerol (sim/exp) BC BE NC NE
True positive (growth/growth) 1165 1124 1195 1154
False positive (growth/no growth) 58 63 28 35
False negative (no growth/growth) 22 63 102 143
True negative (no growth/no growth) 200 195 120 113
  1. See Table 5 caption for description of column headings.