Schematic illustration of the gene screening process. The grey rectangle indicates the processes performed in this study. The red (blue) boxes indicate the data processing flow for the genotype (DNA methylation) data. The solid (dotted) lines indicate data processing flow for the Nsp (Sty) measurements. Sty1 and Sty2 indicate the two combinations of PCs that were used; PC4 for genotype (Figures 4d and 6b)/PC3 for DNA methylation (Figures 5c and 6c), and PC3 for genotype (Figures 4c and 6a)/PC4 for DNA methylation (Figures 5d and 6d).