Figure 5From: Mathematical modeling of GATA-switching for regulating the differentiation of hematopoietic stem cellBifurcation analysis of the four synthesis rates. Tristability property of the system when one of the synthesis rates varies. (A) Rate constant a1; (B) rate constant a2; (C) rate constant b1; and (D) rate constant c1. The curves show the value of a model parameter with which the system maintains three stable steady states. (Blue solid line: the steady state with high GATA-1 level; blue dash line: the steady state with high PU.1 level; red solid/dash/dash-dot line is the level of GATA-1/GATA-2/PU.1 in the primed state).Back to article page