Performance of PANA on synthetic data. A) Performance of control parameters. Average correlation among network pathway profiles (left axis, red polygon) and percentage of links with same simulated expression profiles (right axis, blue polygon) as a function of the accuracy threshold. The upper and lower border of polygons indicate the range of variation at different alpha values. Noise level was set at 0.01. B) Robustness of PANA to experimental noise. Number of selected rules (left axis, red) and percentage of links with same simulated expression profiles (right axis, blue) as a function of the noise in the data. Alpha was set to 0.01 and accuracy to 0.9.