Pathway network inference from gene expression data

BMC Systems Biology

Table 3 List of pathways more frequently associated with the AD pathway reported by Dutta et al [20].

Pathway	KEGG id	Shared Genes with AD pathway	Detected by PANA?
Gap junction	hsa04540	10	YES
GnRH signaling	hsa04912	20	YES
Huntington's disease	hsa05016	99	NO
Adherens junction	hsa04520	2	YES
Axon guidance	hsa04360	11	YES
Dorso-ventral	hsa04320	2	NO
Insulin signaling	hsa04910	10	YES
Long-term depression	hsa04730	11	YES
Long-term potentiation	hsa04720	29	YES
Neurotrophin signaling	hsa04722	12	YES
Oocyte meiosis	hsa04114	18	YES
Pathways in cancer	hsa05200	11	YES
Ubiquitin mediated proteolysis	hsa04120	0	NO

For comparison purpose, the third column shows the shared genes with the AD pathway and the fourth column indicates which associations are also detected by PANA.

ISSN: 1752-0509