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Table 4 Pathways associated with the AD pathway obtained exclusively by PANA method.

From: Pathway network inference from gene expression data

Frequency

Pathway

KEGG id

Shared genes with AD pathway

Literature evidence

4

Citrate cycle (TCA cycle)

hsa00020

4

[46]

4

Pyruvate Metabolism

hsa00620

0

[47, 48]

3

MAPK signaling

hsa04010

19

[49, 50]

3

Peroxisome

hsa04146

0

[51, 52]

3

VEGF signaling

hsa04370

11

[53, 54]

3

Focal adhesion

hsa04510

5

[55]

3

Aldosterone-regulated sodium reabsorption

hsa04960

2

[56, 57]

3

Carbohydrate digestion and absorption

hsa04973

2

[58, 50, 60]

  1. Only those rules that occur at least in three experiments are listed.