Demographics and clinical data | |
---|---|
Age, yrs. | 65 ± 5.5 |
Males, % | 66 |
Body mass index, Kg/m2 | 26.8 ± 5.2 |
Smoking exposure, pack-yrs. | 48.3 ± 29.1 |
Annual Exacerbation rate, year-1 | 0.98 ± 1.6 |
Lung function | |
FEV1, L | 1.26 ± 0.45 |
FEV1, % revers. | 9.5 ± 10.4 |
FEV1/FVC, % | 43.2 ± 11.5 |
Imaging | |
Emphysema, -950HU % | 19.2 ± 12.2 |
Emphysema, extent code | 2.8 ± 1.8 |
Systemic inflammation | |
hsCRP (mg/L) | 8.24 ± 15.0 |
IL6 (pg/mL) | 7.8 ± 36 |
IL8 (pg/mL) | 9.3 ± 5.2 |
CCL18 (ng/mL) | 121.7 ± 46 |
Fibronogen (mg/dL) - | 481.9 ± 107.6 |
TNFA (ng/mL) | 103.2 ± 624 |
SPD (ng/mL) | 120.6 ± 78 |
Induced sputum | |
Total cell count, × 106 | 7.5 ± 1.78 |
Neutrophils, % | 64.8 ± 8.5 |
Eosinophils, % | 3.1 ± 2.04 |
Lymphocytes, % | 25.4 ± 7.9 |