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Table 1 Summary of the characteristics of 140 subjects with sputum gene expression data from the ECLIPSE Cohort.

From: A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease

Demographics and clinical data

Age, yrs.

65 ± 5.5

Males, %

66

Body mass index, Kg/m2

26.8 ± 5.2

Smoking exposure, pack-yrs.

48.3 ± 29.1

Annual Exacerbation rate, year-1

0.98 ± 1.6

Lung function

FEV1, L

1.26 ± 0.45

FEV1, % revers.

9.5 ± 10.4

FEV1/FVC, %

43.2 ± 11.5

Imaging

Emphysema, -950HU %

19.2 ± 12.2

Emphysema, extent code

2.8 ± 1.8

Systemic inflammation

hsCRP (mg/L)

8.24 ± 15.0

IL6 (pg/mL)

7.8 ± 36

IL8 (pg/mL)

9.3 ± 5.2

CCL18 (ng/mL)

121.7 ± 46

Fibronogen (mg/dL) -

481.9 ± 107.6

TNFA (ng/mL)

103.2 ± 624

SPD (ng/mL)

120.6 ± 78

Induced sputum

Total cell count, × 106

7.5 ± 1.78

Neutrophils, %

64.8 ± 8.5

Eosinophils, %

3.1 ± 2.04

Lymphocytes, %

25.4 ± 7.9

  1. Note that all subjects are COPD patients and former smokers. The values represent mean ± standard deviation, frequency or proportion, as appropriate.