TY - JOUR AU - Jones, S. AU - dong Chen, W. AU - Parmigiani, G. AU - Diehl, F. AU - Beerenwinkel, N. AU - Antal, T. AU - Traulsen, A. AU - Nowak, M. A. AU - Siegel, C. AU - Velculescu, V. E. AU - Kinzler, K. W. AU - Vogelstein, B. AU - Willis, J. AU - Markowitz, S. D. PY - 2008 DA - 2008// TI - Comparative lesion sequencing provides insights into tumor evolution JO - Proc Natl Acad Sci USA VL - 105 UR - https://doi.org/10.1073/pnas.0712345105 DO - 10.1073/pnas.0712345105 ID - Jones2008 ER - TY - JOUR AU - Parsons, D. AU - Jones, S. AU - Zhang, X. AU - Lin, J. AU - Leary, R. AU - Angenendt, P. PY - 2008 DA - 2008// TI - An integrated genomic analysis of human glioblastoma multiforme JO - Sciences VL - 321 UR - https://doi.org/10.1126/science.1164382 DO - 10.1126/science.1164382 ID - Parsons2008 ER - TY - JOUR AU - Seshagiri, S. PY - 2012 DA - 2012// TI - recurrent R-spondin fusion in colon cancer JO - Nature VL - 488 UR - https://doi.org/10.1038/nature11282 DO - 10.1038/nature11282 ID - Seshagiri2012 ER - TY - JOUR AU - Sjöblom, T. AU - Jones, S. AU - Wood, L. AU - Parsons, D. AU - Lin, J. PY - 2006 DA - 2006// TI - The Consensus Coding Sequences of Human Breast and Colorectal Cancers JO - Science VL - 314 UR - https://doi.org/10.1126/science.1133427 DO - 10.1126/science.1133427 ID - Sjöblom2006 ER - TY - JOUR AU - Thiagalingam, S. PY - 1996 DA - 1996// TI - Evaluation of chromosome 18q in colorectal cancers JO - Nat Genet VL - 139 UR - https://doi.org/10.1038/ng0796-343 DO - 10.1038/ng0796-343 ID - Thiagalingam1996 ER - TY - JOUR AU - Samuels, Y. AU - Velculescu, V. PY - 2004 DA - 2004// TI - Oncogenic mutations of PIK3CA in human cancers JO - Cell Cycle VL - 3 UR - https://doi.org/10.4161/cc.3.10.1164 DO - 10.4161/cc.3.10.1164 ID - Samuels2004 ER - TY - JOUR AU - Baker, S. PY - 1989 DA - 1989// TI - Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas JO - Science VL - 244 UR - https://doi.org/10.1126/science.2649981 DO - 10.1126/science.2649981 ID - Baker1989 ER - TY - JOUR AU - Armitage, P. AU - Doll, R. PY - 1954 DA - 1954// TI - The age distribution of cancer and a multi-stage theory of carcinogenesis JO - Brit J Cancer VL - 8 UR - https://doi.org/10.1038/bjc.1954.1 DO - 10.1038/bjc.1954.1 ID - Armitage1954 ER - TY - JOUR AU - Armitage, P. AU - Doll, R. PY - 1957 DA - 1957// TI - A two-stage theory of carcinogenesis in relation to the age distribution of human cancer JO - Brit J Cancer VL - 11 UR - https://doi.org/10.1038/bjc.1957.22 DO - 10.1038/bjc.1957.22 ID - Armitage1957 ER - TY - JOUR AU - Attolini, C. AU - Michor, F. PY - 2009 DA - 2009// TI - Evolutionary theory of cancer JO - Ann NY Acad Sci VL - 1168 UR - https://doi.org/10.1111/j.1749-6632.2009.04880.x DO - 10.1111/j.1749-6632.2009.04880.x ID - Attolini2009 ER - TY - JOUR AU - Byrne, H. PY - 2010 DA - 2010// TI - Dissecting cancer through mathematics: from the cell to the animal model JO - Nat Rev Cancer VL - 10 UR - https://doi.org/10.1038/nrc2808 DO - 10.1038/nrc2808 ID - Byrne2010 ER - TY - JOUR AU - Fisher, J. AU - Hollomon, J. PY - 1951 DA - 1951// TI - A hypothesis for the origin of cancerfoci JO - Cancer VL - 4 UR - https://doi.org/3.0.CO;2-7 DO - 3.0.CO;2-7 ID - Fisher1951 ER - TY - JOUR AU - Foo, F. AU - leder, K. AU - Michor, F. PY - 2011 DA - 2011// TI - Stochastic dynamics of cancer initiation JO - Phys Biol VL - 8 UR - https://doi.org/10.1088/1478-3975/8/1/015002 DO - 10.1088/1478-3975/8/1/015002 ID - Foo2011 ER - TY - JOUR AU - Komarova, N. PY - 2005 DA - 2005// TI - Mathematical modeling of tumorigenesis: mission possible JO - Curr Opin Oncol VL - 17 UR - https://doi.org/10.1097/01.cco.0000143681.37692.32 DO - 10.1097/01.cco.0000143681.37692.32 ID - Komarova2005 ER - TY - JOUR AU - Beerenwinkel, N. AU - Antal, T. AU - Dingli, D. AU - Traulsen, A. AU - Kinzler, K. PY - 2007 DA - 2007// TI - Genetic progression and the waiting time to cancer JO - PloS Comput Biol VL - 39 ID - Beerenwinkel2007 ER - TY - JOUR AU - Rick, D. AU - Schmidt, D. AU - Schweinsberg, J. PY - 2009 DA - 2009// TI - A waiting time problem arising from the study of multi-stage carcinigensis JO - ANN APPL PROBAB VL - 19 UR - https://doi.org/10.1214/08-AAP559 DO - 10.1214/08-AAP559 ID - Rick2009 ER - TY - CHAP AU - Frank, S. PY - 2007 DA - 2007// BT - Dynamics of Cancer: Incidence, Inheritance, and Evolution PB - Princeton University Press CY - Oxford ID - Frank2007 ER - TY - JOUR AU - Ritter, G. AU - Wilson, R. AU - Pomper, F. AU - Burmistrov, D. PY - 2003 DA - 2003// TI - The multistage model of cancer develpment: some implications JO - Toxicol Ind Health VL - 19 UR - https://doi.org/10.1191/0748233703th195oa DO - 10.1191/0748233703th195oa ID - Ritter2003 ER - TY - JOUR AU - Meza, R. AU - Hazelton, W. AU - Colditz, G. AU - Moolgavkar, S. PY - 2008 DA - 2008// TI - Analysis of lung cancer incidence in the nurses' health and the health professionals' follow-up studies using a multistage carcinogenesis model JO - Cancer Causes and Control VL - 19 UR - https://doi.org/10.1007/s10552-007-9094-5 DO - 10.1007/s10552-007-9094-5 ID - Meza2008 ER - TY - JOUR AU - Nowak, M. AU - Michor, F. AU - Iwasa, Y. PY - 2003 DA - 2003// TI - The linear process of somatic evolution JO - Proc Natl Acad Sci USA VL - 100 UR - https://doi.org/10.1073/pnas.2535419100 DO - 10.1073/pnas.2535419100 ID - Nowak2003 ER - TY - JOUR AU - Vineis, P. AU - Schatzkin, A. AU - Potter, J. D. PY - 2010 DA - 2010// TI - Models of carcinogenesis: an overview JO - Carcinogenesis VL - 31 UR - https://doi.org/10.1093/carcin/bgq087 DO - 10.1093/carcin/bgq087 ID - Vineis2010 ER - TY - JOUR AU - Iwasa, Y. AU - Michor, F. AU - Komarova, N. AU - Nowak, M. PY - 2005 DA - 2005// TI - Population genetics of tumor suppressor genes JO - J Theor Biol VL - 233 UR - https://doi.org/10.1016/j.jtbi.2004.09.001 DO - 10.1016/j.jtbi.2004.09.001 ID - Iwasa2005 ER - TY - JOUR AU - Meza, R. AU - Jeon, J. AU - Moolgavkar, S. AU - Luebeck, E. PY - 2008 DA - 2008// TI - Age-specific incidence of cancer: Phases, transitions, and biological implications JO - Proc Natl Acad Sci USA VL - 105 UR - https://doi.org/10.1073/pnas.0801151105 DO - 10.1073/pnas.0801151105 ID - Meza2008 ER - TY - JOUR AU - Meza, R. AU - Jeon, J. AU - Renehan, A. G. AU - Luebeck, E. G. PY - 2010 DA - 2010// TI - Colorectal Cancer Incidence Trends in the United States and United Kingdom: Evidence of Right- to Left-Sided Biological Gradients with Implications for Screening JO - Cancer Res VL - 70 UR - https://doi.org/10.1158/0008-5472.CAN-09-4417 DO - 10.1158/0008-5472.CAN-09-4417 ID - Meza2010 ER - TY - JOUR AU - Su-Chan, P. AU - damien, S. i. m. o. n. AU - Krug, J. PY - 2010 DA - 2010// TI - The speed of evolution in large asexual population, Journal of Statistical Physics JO - J Stat Phys VL - 138 UR - https://doi.org/10.1007/s10955-009-9915-x DO - 10.1007/s10955-009-9915-x ID - Su-Chan2010 ER - TY - CHAP AU - Nowak, M. PY - 2008 DA - 2008// BT - Evolutionary Dynamics PB - The Belknap Press of Harvard University Press CY - Oxford ID - Nowak2008 ER - TY - JOUR AU - Nowak, M. AU - Michor, F. AU - Iwasa, Y. PY - 2006 DA - 2006// TI - Genetic instability and clonal expansion JO - J Theor Biol VL - 241 UR - https://doi.org/10.1016/j.jtbi.2005.11.012 DO - 10.1016/j.jtbi.2005.11.012 ID - Nowak2006 ER - TY - JOUR AU - Connolly, R. AU - Kimbell, J. PY - 1994 DA - 1994// TI - Simulation of cell growth governed by stochastic processes: application to clonal growth cancer models JO - YTAAP VL - 124 ID - Connolly1994 ER - TY - JOUR AU - Portier, C. J. AU - Sherman, C. AU - Kopp-Schmeider, A. PY - 2000 DA - 2000// TI - A multistage stochastic models of the cancer process: A general theory for calculating tumor incidence JO - STOCH ENV RES RISK A VL - 14 UR - https://doi.org/10.1007/PL00009780 DO - 10.1007/PL00009780 ID - Portier2000 ER - TY - JOUR AU - Tian, T. AU - Olson, S. AU - Whitacre, J. AU - Harding, A. PY - 2011 DA - 2011// TI - The origins of cancer robustness and evolvability JO - Integrative Biology VL - 3 UR - https://doi.org/10.1039/C0IB00046A DO - 10.1039/C0IB00046A ID - Tian2011 ER - TY - JOUR AU - Luebeck, E. AU - Moolgavkar, S. PY - 2002 DA - 2002// TI - Multistage carcinogenesis and the incidence of colorectal cancer JO - Proc Natl Acad Sci USA VL - 99 UR - https://doi.org/10.1073/pnas.222118199 DO - 10.1073/pnas.222118199 ID - Luebeck2002 ER - TY - JOUR AU - Schinazi, R. PY - 2006 DA - 2006// TI - A stochastic model for cancer risk JO - Genetics VL - 174 UR - https://doi.org/10.1534/genetics.106.059295 DO - 10.1534/genetics.106.059295 ID - Schinazi2006 ER - TY - JOUR AU - Knudson, A. PY - 1971 DA - 1971// TI - Mutation and cancer: statistical study of retinoblastoma JO - Proc Natl Acad Sci USA VL - 68 UR - https://doi.org/10.1073/pnas.68.4.820 DO - 10.1073/pnas.68.4.820 ID - Knudson1971 ER - TY - JOUR AU - Knudson, A. PY - 2001 DA - 2001// TI - Two genetic hits (more or less)to cancer JO - Nat Rev Cancer VL - 1 UR - https://doi.org/10.1038/35101031 DO - 10.1038/35101031 ID - Knudson2001 ER - TY - JOUR AU - Nordling, C. PY - 1953 DA - 1953// TI - A new theory on cancer-inducing mechanism JO - Cancer Res VL - 7 ID - Nordling1953 ER - TY - JOUR AU - Zeig-Owens, R. AU - Gershman, S. AU - Knowlton, R. AU - Jacobson, J. PY - 2009 DA - 2009// TI - Survival and time interval from surgery to start of chemotherapy among colon cancer patients JO - J Registry Manag VL - 36 ID - Zeig-Owens2009 ER - TY - JOUR AU - Berenblum, I. AU - Shubik, P. PY - 1949 DA - 1949// TI - A new quantitative approach to the study of the stages of chemical carcinogenesis in the mouse's skin JO - Brit J Cancer VL - 1 UR - https://doi.org/10.1038/bjc.1947.36 DO - 10.1038/bjc.1947.36 ID - Berenblum1949 ER - TY - JOUR AU - Frank, S. PY - 2004 DA - 2004// TI - Age-specific acceleration of cancer JO - Curr Biol VL - 14 UR - https://doi.org/10.1016/j.cub.2003.12.026 DO - 10.1016/j.cub.2003.12.026 ID - Frank2004 ER - TY - JOUR AU - Kingman, J. PY - 1975 DA - 1975// TI - The first birth problem for an age-dependent branching process JO - Ann prob VL - 3 UR - https://doi.org/10.1214/aop/1176996266 DO - 10.1214/aop/1176996266 ID - Kingman1975 ER - TY - JOUR AU - Moolgavkar, S. AU - Luebeck, E. PY - 1992 DA - 1992// TI - Multistage carcinogenesis: population-based model for colon cancer JO - Cancer Res VL - 84 ID - Moolgavkar1992 ER - TY - JOUR AU - Stransky, B. AU - de Souza, S. J. PY - 2013 DA - 2013// TI - Modeling tumor evolutionary dynamics JO - Front Physiol Comput Physio Medicine VL - 3 ID - Stransky2013 ER - TY - JOUR AU - Bozic, I. AU - Antal, T. AU - Ohtsuki, H. AU - Carter, H. AU - Kim, D. AU - Chen, S. AU - Karchin, R. AU - Kinzler, K. AU - Vogelstein, B. AU - Nowak, M. PY - 2010 DA - 2010// TI - Accumulation of driver and passenger mutations during tumor progression JO - Proc Natl Acad Sci USA VL - 107 UR - https://doi.org/10.1073/pnas.1010978107 DO - 10.1073/pnas.1010978107 ID - Bozic2010 ER - TY - JOUR AU - Yachida, S. AU - Jones, S. AU - Bozic, I. AU - Antal, T. AU - Leary, R. AU - Fu, B. AU - Kamiyama, M. AU - Hruban, R. H. AU - Eshleman, J. R. AU - Nowak, M. A. AU - Velculescu, V. E. AU - Kinzler, K. W. AU - Vogelstein, B. AU - Iacobuzio-Donahue, C. A. PY - 2010 DA - 2010// TI - Distant Metastasis Occurs Late during the Genetic Evolution of Pancreatic Cancer JO - Nature VL - 467 UR - https://doi.org/10.1038/nature09515 DO - 10.1038/nature09515 ID - Yachida2010 ER - TY - CHAP AU - Sun, S. H. AU - Klebaner, F. AU - Tian, T. PY - 2013 DA - 2013// TI - A new model for progression of colorectal cancer BT - 2013 IEEE International Conference on Bioinformatics and Biomedicine, (SCI 2013), Shanghai, China, 18-23 Decenber 2013 PB - International Bioinformatics and Biomedicine CY - Shanghai, China ID - Sun2013 ER - TY - JOUR AU - Beerenwinkel, N. AU - Sullivant, S. PY - 2008 DA - 2008// TI - Markov models for accumulating mutations JO - J Theor Biol VL - 242 UR - https://doi.org/10.1016/j.jtbi.2006.03.013 DO - 10.1016/j.jtbi.2006.03.013 ID - Beerenwinkel2008 ER - TY - JOUR AU - Beerenwinkel, N. AU - Eriksson, N. AU - Sturmfels, B. PY - 2007 DA - 2007// TI - Conjunctive Bayesian networks JO - Bernoulli VL - 13 UR - https://doi.org/10.3150/07-BEJ6133 DO - 10.3150/07-BEJ6133 ID - Beerenwinkel2007 ER - TY - JOUR AU - Rahnenfuhrer, J. AU - Beerenwinkel, N. AU - Schulz, W. AU - Hartmann, C. AU - von Deimling, A. PY - 2005 DA - 2005// TI - Estimating cancer survival and clinical outcome based on genetic tumor progression scores JO - Bioinformatics VL - 21 UR - https://doi.org/10.1093/bioinformatics/bti312 DO - 10.1093/bioinformatics/bti312 ID - Rahnenfuhrer2005 ER - TY - JOUR AU - Wood, L. AU - Parsons, D. AU - Jones, S. AU - Lin, J. AU - Sjoblom, T. AU - Leary, R. PY - 2007 DA - 2007// TI - The genomic landscapes of human breast and colorectal cancers JO - Science VL - 318 UR - https://doi.org/10.1126/science.1145720 DO - 10.1126/science.1145720 ID - Wood2007 ER - TY - STD TI - genome Atlas network TC: Comprehensive molecular characterization of human colon and rectal cancer. Nature. 2012, 487: 330-337. 10.1038/nature11252. ID - ref49 ER - TY - JOUR AU - Jackson, A. AU - Loeb, L. PY - 1998 DA - 1998// TI - The Mutation Rate and Cancer JO - Genetics VL - 148 ID - Jackson1998 ER - TY - JOUR AU - Bozic, I. AU - Reiter, J. AU - Allen, B. AU - Antal, T. AU - Chatterjee, K. AU - Shah, P. AU - Moon, Y. AU - Yaqubie, A. AU - Kelly, N. AU - Le, D. AU - Lipson, E. AU - Chapman, P. AU - Jr, L. D. AU - Vogelstein, B. AU - Nowak, M. A. PY - 2013 DA - 2013// TI - Evolutionary dynamics of cancer in response to targeted combination therapy JO - eLife VL - 2 UR - https://doi.org/10.7554/eLife.00747 DO - 10.7554/eLife.00747 ID - Bozic2013 ER - TY - JOUR AU - Reiter, J. AU - Bozic, I. AU - Allen, B. AU - Chatterjee, K. AU - Nowak, M. PY - 2013 DA - 2013// TI - The effect of one additional driver mutation on tumor progression JO - Evol Appl VL - 6 UR - https://doi.org/10.1111/eva.12020 DO - 10.1111/eva.12020 ID - Reiter2013 ER - TY - JOUR AU - Sawyers, C. PY - 2004 DA - 2004// TI - Targeted cancer therapy JO - Nature VL - 432 UR - https://doi.org/10.1038/nature03095 DO - 10.1038/nature03095 ID - Sawyers2004 ER - TY - JOUR AU - Imai, K. AU - Takaoka, A. PY - 2006 DA - 2006// TI - Comparing antibody and smallmolecule therapies for cancer JO - Nat Rev Cancer VL - 6 UR - https://doi.org/10.1038/nrc1913 DO - 10.1038/nrc1913 ID - Imai2006 ER - TY - JOUR AU - Bozicl, I. AU - Allen, B. AU - Nowak, M. A. PY - 2012 DA - 2012// TI - Dynamics of targeted cancer therapy, Trends in Molecular Medicine JO - Trends Mol Med VL - 18 UR - https://doi.org/10.1016/j.molmed.2012.04.006 DO - 10.1016/j.molmed.2012.04.006 ID - Bozicl2012 ER -