Figure 7From: Complex-based analysis of dysregulated cellular processes in cancerDifferential PPI network constructed for normal vs PDAC. (a) Largest component of the network composed of 519 interactions among 558 proteins, out of which 439 (or 84.5%) interactions showed a decrease in co-expression from normal to PDAC (red interactions indicate increase from normal to PDAC while green indicate decrease); (b) several genes are silenced by ubiquitination and sumoylation in PDAC; (c) several known drug targets are centered around interactions showing increase in co-expression.Back to article page