BMC Systems Biology

Table 2 The performance of eleven scoring methods in predicting essential proteins, evaluated by the precision of essential proteins in the top ranked list.

From: cytoHubba: identifying hub objects and sub-networks from complex interactome

Top		10	20	30	40	50	60	70	80	90	100
Local-based Method
	MCC	0.90	0.90	0.87	0.82	0.76	0.73	0.71	0.69	0.70	0.71
	DMNC	0.80	0.80	0.73	0.68	0.64	0.58	0.54	0.53	0.56	0.54
	MNC	0.60	0.50	0.50	0.47	0.48	0.52	0.53	0.54	0.51	0.50
	Degree	0.70	0.55	0.47	0.42	0.46	0.47	0.49	0.47	0.46	0.44
Global-based Method
	EPC	0.50	0.50	0.47	0.45	0.48	0.45	0.43	0.42	0.41	0.39
	BottleNeck	0.60	0.60	0.43	0.47	0.44	0.42	0.44	0.44	0.43	0.43
	EcCentricity	0.30	0.45	0.40	0.45	0.44	0.47	0.44	0.41	0.37	0.39
	Closeness	0.50	0.45	0.47	0.50	0.50	0.45	0.46	0.47	0.48	0.48
	Radiality	0.50	0.35	0.43	0.50	0.48	0.43	0.47	0.47	0.49	0.48
	Betweenness	0.60	0.55	0.50	0.50	0.46	0.45	0.46	0.47	0.46	0.43
	Stress	0.60	0.55	0.43	0.47	0.46	0.48	0.49	0.45	0.42	0.43

Back to article page

ISSN: 1752-0509

Contact us

General enquiries: ORSupport@springernature.com