Figure 1

The effect of downstream genes on regulatory genes in synthetic genetic circuits. (a) Synthetic genetic circuits in a cell. Regulatory genes of synthetic genetic circuits have an effect on downstream genes, such as reporter genes or genes in natural genetic circuits. (b) Competition for regulatory-protein-binding sites among genes encoding regulatory proteins and an additional reporter gene in synthetic genetic circuits. (c) Protein degradation systems in a cell. Proteins often share the same degradation system.