Figure 5

Relationship of the effects of impedance between electric circuit and Genetic circuit. (a) Relationship of the effects of impedance between electric circuit and genetic circuit. In electric circuit, downstream component outputs voltage in proportion to downstream input consumed by downstream input impedance. (b-e) Genetic circuit models of the effects of impedance. (b) The low output impedance model of genetic circuit models. (c) The high output impedance model of genetic circuit models. (d) The low input impedance model of genetic circuit models. (e) The high input impedance model of genetic circuit models. AraC and LacI form regulatory genes. GFP is the downstream gene. AraC protein and LacI protein represented by colored circles are accommodated in the binding sites of the GFP promoter. Numbers of colored circles represent concentrations of regulatory proteins. Low output impedance and high input impedance are suitable to keep dynamics of regulatory genes even after connection of the downstream gene.