TY - JOUR AU - Yang, Tzu-Hsien AU - Wang, Chung-Ching AU - Hung, Po-Cheng AU - Wu, Wei-Sheng PY - 2014 DA - 2014/12/08 TI - cis MEP: an integrated repository of genomic epigenetic profiles and cis-regulatory modules in Drosophila JO - BMC Systems Biology SP - S8 VL - 8 IS - 4 AB - Cis-regulatory modules (CRMs), or the DNA sequences required for regulating gene expression, play the central role in biological researches on transcriptional regulation in metazoan species. Nowadays, the systematic understanding of CRMs still mainly resorts to computational methods due to the time-consuming and small-scale nature of experimental methods. But the accuracy and reliability of different CRM prediction tools are still unclear. Without comparative cross-analysis of the results and combinatorial consideration with extra experimental information, there is no easy way to assess the confidence of the predicted CRMs. This limits the genome-wide understanding of CRMs. SN - 1752-0509 UR - https://doi.org/10.1186/1752-0509-8-S4-S8 DO - 10.1186/1752-0509-8-S4-S8 ID - Yang2014 ER -