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Table 1 The 27 predicted cooperative TF pairs

From: Identifying cooperative transcription factors in yeast using multiple data sources

Ranking TF1 TF2 Consistent with existing methods' predictions Having PPIs? Co-annotated MIPS functional categories
1 Reb1 YDR026C [3] -- --
2 Fkh2 Fkh1 [1],[2],[3],[4],[7],[8],[38] Y mitotic cell cycle and cell cycle control; budding, cell polarity and filament formation
3 Tye7 Cbf1 [3] Y metabolism
4 Dig1 Ste12 [3],[7],[20] Y protein folding; pheromone response, mating-type determination, sex-specific proteins; budding, cell polarity and filament formation
5 Pdr3 Pdr1 --- Y DNA binding; chemical agent resistance; detoxification
6 Swi6 Mbp1 [2],[3],[4],[5],[7],[20],[38] Y DNA synthesis and replication; mitotic cell cycle and cell cycle control; protein with binding function or co-factor requirement (structural or catalytic)
7 Swi6 Swi4 [2],[3],[4],[5],[7],[9],[20],[38] Y G1/S transition of mitotic cell cycle
8 Dal80 Gln3 --- Y regulation of nitrogen metabolism
9 Gln3 Gat1 [3] Y regulation of nitrogen metabolism
10 Dal80 Gat1 --- -- regulation of nitrogen metabolism
11 Pho4 Cbf1 --- Y metabolism; DNA binding
12 Pho4 Tye7 --- -- metabolism
13 Hap3 Hap2 [20] Y regulation of C-compound and carbohydrate metabolism
14 Gal80 Gal4 --- Y regulation of C-compound and carbohydrate metabolism
15 Met31 Met32 [3] Y metabolism of methionine; metabolism of cysteine; regulation of amino acid metabolism; regulation of nitrogen, sulfur and selenium metabolism; DNA binding
16 Msn4 Msn2 [3] Y DNA binding; stress response
17 Rap1 Fhl1 [3],[8],[20] Y ---
18 Tec1 Ste12 [3] Y budding, cell polarity and filament formation
19 Swi6 Stb1 [3],[7] Y G1/S transition of mitotic cell cycle
20 Hap2 Hap5 [8] Y regulation of C-compound and carbohydrate metabolism
21 Nrg1 Nrg2 --- Y protein with binding function or co-factor requirement (structural or catalytic); budding, cell polarity and filament formation
22 Hap3 Hap5 [8],[20] Y regulation of C-compound and carbohydrate metabolism
23 Swi4 Stb1 [3],[4],[7] Y G1/S transition of mitotic cell cycle
24 Swi5 Ace2 [2],[3],[4],[7],[9] Y G1 phase of mitotic cell cycle
25 Sok2 Phd1 [3] Y budding, cell polarity and filament formation
26 Hap5 Hap4 --- Y regulation of C-compound and carbohydrate metabolism
27 Mbp1 Swi4 [1],[2],[3],[6],[7],[9] Y mitotic cell cycle and cell cycle control