Skip to main content
Figure 15 | BMC Systems Biology

Figure 15

From: Robustness analysis on interspecies interaction network for iron and glucose competition between Candida albicans and zebrafish during infection

Figure 15

The sub-network for the iron host-pathogen interspecies interaction network in the adhesion stage. There were 273 interspecies interactions between C. albicans and zebrafish in the iron host-pathogen interspecies interaction network in the adhesion stage. There were nine iron-related virulence proteins identified as significantly interactive for C. albicans (pink triangles) and 10 iron-related immune proteins for zebrafish (pink circles). The major functional modules for C. albicans in this early infection stage were identified as adhesion activity (tup1, asc1), metal ion transport (ccc2), reductase activity (fre10), and cellular iron ion homeostasis (hap43, mnn2), while the main activities for zebrafish were identified as the immune response (jmjd6, hamp1), metal ion transport (atp7a, glrx5), and hematopoiesis-related processes (hmox1, tfr1a, ndfip1, alas2, hpx).

Back to article page

BMC Systems Biology

ISSN: 1752-0509

Contact us