Table 2 Differential equations for the basic apoptosis network N₁ (Figure 1)

1

$\frac{d}{dt}\mathsf{\text{Casp}}6$

- [Casp6]·rc₁₁ + [Casp9]·rc₁₂

2

$\frac{d}{dt}\mathsf{\text{CDK}}1$

+[Wee1]·rc₁₃ - [CDK1]·rc₁₄

3

$\frac{d}{dt}\mathsf{\text{Wee}}1$

- [Wee1]·rc₁₃

4

$\frac{d}{dt}\mathsf{\text{JNK}}$

- [JNK]·rc₁₅ + [EGFR]·rc₁₇

5

$\frac{d}{dt}\mathsf{\text{BID}}$

- [BID]·rc₁₆ - [BID]·rc₂₅

6

$\frac{d}{dt}\mathsf{\text{EGFR}}$

- [EGFR]·rc₁₇ - [EGFR]·rc₃₂;

7

$\frac{d}{dt}\mathsf{\text{PUMA}}$

- [PUMA]·rc₁₉ + [p53]·rc₂₇

8

$\frac{d}{dt}\mathsf{\text{Casp}}3$

- [Casp3]·rc₁ + [XIAP]·rc₂ + [SMAC]·rc₄ + [Casp8]·rc₇ - [Casp3]·rc₈ +[Casp9]·rc₉ +[Casp6]·rc₁₁ + [MOMP]·rc₃₀

9

$\frac{d}{dt}\mathsf{\text{Casp9}}$

- [Casp9]·rc₉ - [Casp9]·rc₁₂ + [PUMA]·rc₁₉ - [Casp9]·rc₂₄ + [BCL2]·rc₂₆

10

$\frac{d}{dt}\mathsf{\text{HER2}}$

- [HER2]·rc₂₀ - [HER2]·rc₃₁

11

$\frac{d}{dt}\mathsf{\text{Casp8}}$

- [Casp8]·rc₃ + [RIP1]·rc₆ - [Casp8]·rc₇ + [Casp3]·rc₈ + [BID]·rc₂₅ +[EGFR]·rc

12

$\frac{d}{dt}\mathsf{\text{Apop}}$

+[Casp3]·rc₁

13

$\frac{d}{dt}\mathsf{\text{XIAP}}$

- [XIAP]·rc₂ + [SMAC]·rc2₁ + [Casp9]·rc₂₄ + [HER2]·rc₃₁

14

$\frac{d}{dt}\mathsf{\text{SMAC}}$

+[Casp8]·rc₃ - [SMAC]·rc₄ + [BCL2]·rc₅ - [SMAC]·rc₂₁ + [MOMP]·rc₂₉

15

$\frac{d}{dt}\mathsf{\text{BCL2}}$

- [BCL2]·rc₅ + [p53]·rc₁₀ + [CDK1]·rc₁₄ + [JNK]·rc₁₅ +[BID]·rc₁₆ +[STAT3]·rc₂₂ - [BCL2]·rc₂₆

16

$\frac{d}{dt}\mathsf{\text{RIP1}}$

- [RIP1]·rc₆ + [TNFR]·rc₂₃

17

$\frac{d}{dt}\mathsf{\text{P53}}$

- [p53]·rc₁₀ + [AKT]·rc₁₈ - [p53]·rc₂₇

18

$\frac{d}{dt}\mathsf{\text{AKT}}$

- [AKT]·rc₁₈ + [HER2]·rc₂₀

19

$\frac{d}{dt}\mathsf{\text{STAT3}}$

- [STAT3]·rc₂₂

20

$\frac{d}{dt}\mathsf{\text{TNFR}}$

- [TNFR]·rc₂₃

21

$\frac{d}{dt}\mathsf{\text{DAPK}}1$

- [DAPK1]·rc₂₈

22

$\frac{d}{dt}\mathsf{\text{MOMP}}$

+[DAPK1]·rc₂₈ - [MOMP]·rc₂₉ - [MOMP]·rc₃₀