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Table 2 Table 1

From: Transcription factor and microRNA-regulated network motifs for cancer and signal transduction networks

  ARL FBL FFL bi-fan SIM
A The total number of the five motif types identified for cancer networks and STNs
Cancer networks
Pathways in cancer 0 0 1 73 27
AML 0 0 0 9 12
Glioma 0 0 0 9 6
Melanoma 0 0 0 1 4
NSCLC 0 1 2 4 7
PC 0 0 1 0 5
RCC 0 0 1 0 3
Signal transduction networks (STNs)
Erbb 0 0 5 69 17
FoxO 0 0 3 0 3
Hippo 0 0 2 0 8
Jak-Stat 0 0 0 4 3
Mapk 0 0 1 6 32
PI3k-Akt 0 0 1 1 10
Rap1 0 0 0 1 13
Ras 0 0 2 15 18
TGF_Beta 0 0 0 1 7
TNF 0 0 0 1 11
TCS 0 0 0 3 35
VEGF 0 0 2 0 5
Wnt 0 0 11 0 7
* TCS denotes the Two-component system
B The total number of SIM motifs identified in cancer networks and STNs
Cancer networks SIM
Basal cell carcinoma 1
Bladder cancer 1
Chronic myeloid leukemia 4
Colorectal cancer 4
Endometrial cancer 4
Pancreatic cancer 8
Small cell lung cancer 2
Signal transduction networks (STNs) 9
Calcium signaling 3
Hedgehog 6
HIF-1 6
mTOR 10
NFkB 2
Notch 2
Phosphatidylinositol signaling system