Skip to main content

Table 2 Significantly enriched terms (using ToppGene) in the 100 genes that have the largest regression coefficients for each profile

From: Investigating the utility of clinical outcome-guided mutual information network in network-based Cox regression

Profile Category ID Name p-value Adjusted p-value Count Total
CNA GO:BP GO:0048706 embryonic skeletal system development 5.99E-06 1.25E-02 7 129
  GO:BP GO:0048704 embryonic skeletal system morphogenesis 1.43E-05 1.50E-02 6 98
  GO:BP GO:0009952 anterior/posterior pattern specification 2.17E-05 1.52E-02 8 217
  Disease ctd:D010051 Ovarian Neoplasms 5.24E-04 2.84E-02 4 78
  Disease ctd:D002277 Carcinoma 7.42E-03 3.66E-02 4 161
  GO:BP GO:0031442 positive regulation of mRNA 3'-end processing 7.94E-05 4.15E-02 3 16
  GO:BP GO:0031440 regulation of mRNA 3'-end processing 1.15E-04 4.80E-02 3 18
mRNA GO:MF GO:0004568 chitinase activity 4.80E-06 1.78E-03 3 7
  GO:BP GO:0006032 chitin catabolic process 4.83E-06 4.94E-03 3 7
  GO:BP GO:0006030 chitin metabolic process 4.83E-06 4.94E-03 3 7
  GO:BP GO:1901072 glucosamine-containing compound catabolic process 7.70E-06 5.24E-03 3 8
  GO:MF GO:0086080 protein binding involved in heterotypic cell-cell adhesion 8.12E-05 1.50E-02 2 3
  GO:MF GO:0098631 protein binding involved in cell adhesion 1.62E-04 1.50E-02 2 4
  GO:MF GO:0098632 protein binding involved in cell-cell adhesion 1.62E-04 1.50E-02 2 4
  GO:BP GO:0046348 amino sugar catabolic process 3.86E-05 1.97E-02 3 13
  GO:MF GO:0008061 chitin binding 2.69E-04 1.99E-02 2 5
  GO:MF GO:0030492 hemoglobin binding 7.45E-04 4.61E-02 2 8
METH GO:CC GO:0030424 axon 9.91E-06 1.95E-03 11 409
  GO:CC GO:0043025 neuronal cell body 2.06E-04 1.57E-02 10 478
  GO:CC GO:0043195 terminal bouton 3.15E-04 1.57E-02 4 62
  GO:CC GO:0036477 somatodendritic compartment 3.19E-04 1.57E-02 12 705
  GO:CC GO:0043005 neuron projection 4.07E-04 1.61E-02 14 945
  GO:CC GO:0044297 cell body 5.10E-04 1.68E-02 10 536
  GO:CC GO:0032983 kainate selective glutamate receptor complex 7.48E-04 2.11E-02 2 8
  GO:MF GO:0004952 dopamine neurotransmitter receptor activity 2.80E-04 4.01E-02 2 5
  GO:MF GO:0001965 G-protein alpha-subunit binding 3.95E-04 4.01E-02 3 27
  GO:MF GO:0015075 ion transmembrane transporter activity 4.14E-04 4.01E-02 13 819
  GO:MF GO:0022857 transmembrane transporter activity 5.21E-04 4.01E-02 14 951
  GO:MF GO:0015026 coreceptor activity 5.98E-04 4.01E-02 3 31
  GO:MF GO:0022891 substrate-specific transmembrane transporter activity 7.68E-04 4.29E-02 13 875
  GO:MF GO:0022892 substrate-specific transporter activity 9.57E-04 4.58E-02 14 1012