Skip to main content

Table 2 Significantly enriched terms (using ToppGene) in the 100 genes that have the largest regression coefficients for each profile

From: Investigating the utility of clinical outcome-guided mutual information network in network-based Cox regression

Profile

Category

ID

Name

p-value

Adjusted p-value

Count

Total

CNA

GO:BP

GO:0048706

embryonic skeletal system development

5.99E-06

1.25E-02

7

129

 

GO:BP

GO:0048704

embryonic skeletal system morphogenesis

1.43E-05

1.50E-02

6

98

 

GO:BP

GO:0009952

anterior/posterior pattern specification

2.17E-05

1.52E-02

8

217

 

Disease

ctd:D010051

Ovarian Neoplasms

5.24E-04

2.84E-02

4

78

 

Disease

ctd:D002277

Carcinoma

7.42E-03

3.66E-02

4

161

 

GO:BP

GO:0031442

positive regulation of mRNA 3'-end processing

7.94E-05

4.15E-02

3

16

 

GO:BP

GO:0031440

regulation of mRNA 3'-end processing

1.15E-04

4.80E-02

3

18

mRNA

GO:MF

GO:0004568

chitinase activity

4.80E-06

1.78E-03

3

7

 

GO:BP

GO:0006032

chitin catabolic process

4.83E-06

4.94E-03

3

7

 

GO:BP

GO:0006030

chitin metabolic process

4.83E-06

4.94E-03

3

7

 

GO:BP

GO:1901072

glucosamine-containing compound catabolic process

7.70E-06

5.24E-03

3

8

 

GO:MF

GO:0086080

protein binding involved in heterotypic cell-cell adhesion

8.12E-05

1.50E-02

2

3

 

GO:MF

GO:0098631

protein binding involved in cell adhesion

1.62E-04

1.50E-02

2

4

 

GO:MF

GO:0098632

protein binding involved in cell-cell adhesion

1.62E-04

1.50E-02

2

4

 

GO:BP

GO:0046348

amino sugar catabolic process

3.86E-05

1.97E-02

3

13

 

GO:MF

GO:0008061

chitin binding

2.69E-04

1.99E-02

2

5

 

GO:MF

GO:0030492

hemoglobin binding

7.45E-04

4.61E-02

2

8

METH

GO:CC

GO:0030424

axon

9.91E-06

1.95E-03

11

409

 

GO:CC

GO:0043025

neuronal cell body

2.06E-04

1.57E-02

10

478

 

GO:CC

GO:0043195

terminal bouton

3.15E-04

1.57E-02

4

62

 

GO:CC

GO:0036477

somatodendritic compartment

3.19E-04

1.57E-02

12

705

 

GO:CC

GO:0043005

neuron projection

4.07E-04

1.61E-02

14

945

 

GO:CC

GO:0044297

cell body

5.10E-04

1.68E-02

10

536

 

GO:CC

GO:0032983

kainate selective glutamate receptor complex

7.48E-04

2.11E-02

2

8

 

GO:MF

GO:0004952

dopamine neurotransmitter receptor activity

2.80E-04

4.01E-02

2

5

 

GO:MF

GO:0001965

G-protein alpha-subunit binding

3.95E-04

4.01E-02

3

27

 

GO:MF

GO:0015075

ion transmembrane transporter activity

4.14E-04

4.01E-02

13

819

 

GO:MF

GO:0022857

transmembrane transporter activity

5.21E-04

4.01E-02

14

951

 

GO:MF

GO:0015026

coreceptor activity

5.98E-04

4.01E-02

3

31

 

GO:MF

GO:0022891

substrate-specific transmembrane transporter activity

7.68E-04

4.29E-02

13

875

 

GO:MF

GO:0022892

substrate-specific transporter activity

9.57E-04

4.58E-02

14

1012