Figure 10

P _sy variation influences cell subpopulation dynamics. A color-code identical to that of Figure 2 panel C1 was defined for P _sy variation (see Table 2), and model outputs were then consequently colored. Panels report the colored visualizations of subpopulations: A-CSCs, B-PCs, C-TCs, and D-DCs. Results revealed that P _sy is responsible for a switching-like behavior, which discriminates between tumorigenesis (red and green lines) and unsustainable tumor growth (black lines). Output data are expressed using a logarithmic scale to reduce their wide range to a more manageable size.