Skip to main content
Figure 12 | BMC Systems Biology

Figure 12

From: A versatile mathematical work-flow to explore how Cancer Stem Cell fate influences tumor progression

Figure 12

Switching characterization. Scatter plots of CSCs at time t = 200 were produced considering also the other key parameters and two ad hoc combinations of them. Specifically: panel A reports CSCs versus ω CSC , panel B refers to CSCs versus η1, panel C shows CSCs versus P sy ω CSC , and panel D displays CSCs versus P sy ω CSC − η1. All plots are colored using the P sy color-code previously defined, and they confirm the central role of this parameter. Indeed, ω CSC and η1 variations considered individually are not able to characterize the switch. On the other hand, combining these parameters with P sy it is possible to better characterize the switch when P sy assumes intermediate values.

Back to article page