Figure 13From: A versatile mathematical work-flow to explore how Cancer Stem Cell fate influences tumor progressionP sy bifurcation plots and CSC dynamics. Bifurcation analysis on model (1) revealed that the system undergoes a transcritical bifurcation as P sy varies. Two steady states exist: E0 (trivial state) and E1 (positive state). The former one correspond to an unsustainable tumor growth, while the latter describes tumor growth and stabilization. When P sy reaches the transcritical bifurcation point P ∗ , E0 and E1 collide and interchange their stability conditions.Back to article page