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Table 1 Comparisons between StochKit, the SSA implementation on the R-System and our approach for a MM reaction scheme.

From: Modelling non-Markovian dynamics in biochemical reactions

 

Gecode

R-System

StochKit

2

Time

Iterations

Time

Iterations

Time Iterations

100

0.28

500

1.10

10412.40

0.04 5

101

0.35

500

28.78

99929.2

0.11 48

102

0.39

500

1855.92

990849.5

0.26 500

103

0.43

500

-

-

0.78 5000

104

0.42

500

-

-

7.75 50000

105

0.39

500

-

-

77.50 500000

  1. Times in seconds reported correspond to the average of 10 runs. Constants k1 and k3 were set to 10 and k2 varies as shown in the table. The initial concentrations of S and E were set to 100000 and 100 molecules, respectively.