Figure 11
From: Disentangling the multigenic and pleiotropic nature of molecular function
Semantic distance between multi-pathway genes' functional profiles. The solid blue and green lines show the frequency of distances between pairs of GO terms, within each of the pathway profiles. The dashed lines show the frequency of semantic distances between random annotation pairs. The orange line shows pairwise GO annotation distances between functional profiles of pathways sharing a multi-pathway gene. Comparison to the solid blue line shows increased semantic distances between the functional profiles of multi-pathway genes.