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Figure 11 | BMC Systems Biology

Figure 11

From: Identification of network-based biomarkers of cardioembolic stroke using a systems biology approach with time series data

Figure 11

Apoptosis and survival NGF activation of NF-kB which is the fourth scored pathway map in MetaCore enrichment analysis results. Nerve growth factor (NGF) involved in neuron survival and differentiation, and the NF-kB signal generated by receptors of tyrosinekinase (TrkA) and the tumor necrosis factor receptor (NGFR) exerts neuroprotective effects. Ubiquitin was down-regulated in stoke samples at 3, 5, 24 hours and overall stroke samples as compared with control. GAB1 was up-regulated in overall stoke samples.

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