Skip to main content
Figure 6 | BMC Systems Biology

Figure 6

From: Knowledge-fused differential dependency network models for detecting significant rewiring in biological networks

Figure 6

Rewiring of apoptosis pathway in breast cancer patients with and without recurrence. Red edges are unique connections in patients with recurrent breast cancer, where inflammatory/immune response genes IL1B, NFκB and TNFα that are all linked to increased resistance to breast cancer treatment were found. Green edges are unique connections in patients with breast cancer that did not recur, where paths to both anti-apoptotic XIAP/AKT2 and proapoptotic BAX and BAD were formed.

Back to article page