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Table 2 Pegasus predictions on GBM RNA-Seq data

From: Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer

5’ Gene partner 3’ Gene partner Pegasus driver score Recurrence
YEATS4 XRCC6BP1 0.9598 1
EIF4H GTF2I 0.9440 1
ASH1L C1orf61 0.9256 1
SEC61G EGFR 0.9234 4
BCAN NTRK1 0.9182 1
EGFR VOPP1 0.9130 2
EGFR SEPT14 0.9042 6
TDRD3 ESD 0.8959 1
TFG GPR128 0.8880 4
PPP2R2B CCT3 0.8699 1
TBC1D14 HTRA3 0.8697 1
FGFR3 TACC3 0.8442 3
LANCL2 SEPT14 0.8428 3
  1. Pegasus top driver scores (PDS > 0.8) predicts 46% of known driver gene fusions in GBM data from TCGA cohort. Recurrence is assessed on the basis of gene fusion frequency reported in Frattini et al. and Brennar et al.