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Table 1 Estimation of the expected risk

From: A Bayesian active learning strategy for sequential experimental design in systems biology

Risk Cost Experiment Observe proteins
771 1200 Delete gene 7 3-8
1196 850 Decrease gene 7 RBS activity 3-8
1290 750 Knock down gene 7 3-8
1957 850 Decrease gene 7 RBS activity 3-7
2254 850 Decrease gene 7 RBS activity 7-8
2554 1200 Delete gene 9 3-8
2867 750 Knock down gene 7 8-9
4647 1200 Delete gene 7 8-9
4798 850 Decrease gene 7 RBS activity 8-9
4928 850 Decrease gene 7 RBS activity 5-8
  1. Estimation of the expected risk at a certain stage of the experimentation, ten lowest values. There is consistency in the type of experiment to be conducted (targeting gene 7 which expression impacts on a big part of the network) and the quantities to measure (protein 8 almost all the time and protein 3 quite often). Figure 4 illustrate this point further.