Functional PPI network for skeletal tissue. (a) The PPI network with different coloured nodes (showing their influence over different physiological parameters) connected through their interactors extracted from STRING data base. Nodes uniquely related to a particular physiological parameter are: Red nodes—related to body weight, green nodes—related to blood glucose, blue nodes—related to anti-inflammatory cytokines and reddish yellow nodes— related to pro-inflammatory cytokines. Magenta coloured nodes are for genes influencing more than one physiological parameter. (b) The power law distribution of the network showing its “scale-free” property.