Figure 2From: Membrane related dynamics and the formation of actin in cells growing on micro-topographies: a spatial computational model Simplified schema of signal transduction by which the topographical influence of the surface activates cofilin via the integrin-Rho-ROCK-pathway, finally inhibiting the actin polymerization. The blue arrows express the total protein expression on the micro-pillared surface in relation to the planar reference based on the biological data obtained from the wet-lab experiments (see Results).Back to article page