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Figure 3 | BMC Systems Biology

Figure 3

From: Membrane related dynamics and the formation of actin in cells growing on micro-topographies: a spatial computational model

Figure 3

Densitometric analysis of the protein expression of Rho A, ROCK-1 and vinculin in MG-63 osteoblasts after 3 h (Rho A only) and 24 h. On the micro-pillared surface (P-5 × 5 × 5), Rho A expression is significantly lower compared to the planar reference (Ref). Vinculin expression is also lowered, ROCK-1 expression changes are not significant. (Mean ± SD, unpaired t-Test, n = 6 for Rho A, n = 3 for ROCK-1, *** p < 0.001) (Molecular Imager®; ChemiDoc™ XRS, Quantity One®; 1-D analysis software, Bio-Rad).

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