Figure 7

Relation of filament size to amounts of active cofilin and other parameters. Each marker indicates the result of a simulation run with different parameters. Colors denote parameters related to the cofilin activation mechanism, marker types distinguish simulations of pillar structure systems (triangles) and planar surfaces (circles), and larger markers indicate simulations with 200 initial integrin entities vs. 100 for the smaller markers (mostly to be found above the former). More active cofilin thus coincides with shorter filaments.