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Table 4 Top genes ranked by the RWR algorithm (using HG genes with high Odds Ratio scores as seeds) and their average semantic similarity to two meiotic recombination related GO terms

From: Finding trans-regulatory genes and protein complexes modulating meiotic recombination hotspots of human, mouse and yeast

  Yeast Human Mouse
Rank Genes Similarity Genes Similarity Genes Similarity
1 YDR176W 0.354 KPNA2 0.712 EP300 0.303
2 YNL118C 0.292 UBC 0.806 CREBBP 0.504
3 YBR155W 0.309 FBXW11 0.458 JUN 0.509
4 YDL076C 0.259 HDAC1 0.502 HCFC1 0.463
5 YKR086W 0.224 HDAC3 0.466 YWHAB 0.266
6 YGR200C 0.31 CREBBP 0.378 ESR1 0.482
7 YBR160W 0.659 GLI3 0.396 TAT 0.267
8 YLR103C 0.447 GLI1 0.307 RELA 0.396
9 YJR066W 0.608 GLI2 0.457 NFYB 0.37
10 YDR388W 0.144 SIN3A 0.67 SOX10 0.42
Average   0.361   0.515   0.398
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