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Table 4 Top genes ranked by the RWR algorithm (using HG genes with high Odds Ratio scores as seeds) and their average semantic similarity to two meiotic recombination related GO terms

From: Finding trans-regulatory genes and protein complexes modulating meiotic recombination hotspots of human, mouse and yeast

 

Yeast

Human

Mouse

Rank

Genes

Similarity

Genes

Similarity

Genes

Similarity

1

YDR176W

0.354

KPNA2

0.712

EP300

0.303

2

YNL118C

0.292

UBC

0.806

CREBBP

0.504

3

YBR155W

0.309

FBXW11

0.458

JUN

0.509

4

YDL076C

0.259

HDAC1

0.502

HCFC1

0.463

5

YKR086W

0.224

HDAC3

0.466

YWHAB

0.266

6

YGR200C

0.31

CREBBP

0.378

ESR1

0.482

7

YBR160W

0.659

GLI3

0.396

TAT

0.267

8

YLR103C

0.447

GLI1

0.307

RELA

0.396

9

YJR066W

0.608

GLI2

0.457

NFYB

0.37

10

YDR388W

0.144

SIN3A

0.67

SOX10

0.42

Average

 

0.361

 

0.515

 

0.398